Carbonic anhydrase activity in mitochondria from rat liver.

Testosterone-induced, sulfonamide-resistant carbonic anhydrase isozyme of rat liver is indistinguishable from skeletal muscle carbonic anhydrase III.

Three isozymes of carbonic anhydrase, CA I, CA II and CA III, have been characterized from the tissues of a variety of vertebrate species. CA I (low-activity, sulfonamide-sensitive form) has been found mainly in red cells but also occurs in other tissues (e.g., rumen epithelium, caecum, colonic mucosa, pituitary gland, ciliary body), CA II (high-activity, sulfonamide-sensitive form) is found in...

Blood carbonic anhydrase activity in the newborn.

Logan, R. W., Crooks, S. M., Hutchison, J. H., and Kerr, M. M. (1973). Archives of Disease in Childhood, 48, 256. Blood carbonic anhydrase activity in the newborn. Erythrocyte carbonic anhydrase activity was measured in 7 adults, 12 mature newborn infants, 12 preterm low birthweight infants, 9 'dysmature' infants, 33 infants with the respiratory distress syndrome (RDS), and 5 infants who had re...

Targeting carbonic anhydrase IX activity and expression.

Metastatic tumors are often hypoxic exhibiting a decrease in extracellular pH (~6.5) due to a metabolic transition described by the Warburg Effect. This shift in tumor cell metabolism alters the tumor milieu inducing tumor cell proliferation, angiogenesis, cell motility, invasiveness, and often resistance to common anti-cancer treatments; hence hindering treatment of aggressive cancers. As a re...

Carbonic Anhydrase Activity during Embryonic Development

The Effect of Resveratrol against Acrolein Toxicity in Mitochondria isolated from Rat Liver

Introduction: Acrolein is an important environmental, food and water pollutant that plays an important role in the development of several diseases. Resveratrol is a phenolic compound with antioxidant properties found in fruits such as grapes, berries and peanuts. The purpose of this study was to evaluate the protective effect of resveratrol in preventing Acrolein-induced toxicity in isolated mi...